"And Yitzchak sowed in that land, and he found in that year a hundredfold, and the Lord blessed him" (Bereishis 26:12). The verse reveals to us that even though a great famine struck all the inhabitants of the land, nevertheless, Yitzchak miraculously prospered. Amazingly, his land produced such a bountiful harvest that if filled one hundred vast storehouses. Therefore, "HaShem blessed him," so that no one would cast a jealous eye upon him. The secret of Yitzchak's phenomenal wealth was that he carefully tithed his produce according to the proper Torah requirements. The Torah guarantees success to all those who separate tithes, "'Test me, please in this,' said HaShem, 'if I will not open for you windows in heavens and pour countless blessings upon you.'"
HaShem rewarded Yitzchak with great wealth and prosperity, during a famine, because he meticulously tithed his produce, "And the man became great, and he grew constantly greater until he had grown very great" (Bereishis 26:13).
Envision Yitzchak sowing his field in the days of famine. As he tends to his field, he has in mind to tithe the produce. See his fruitful fields sprout with a phenomenally plentiful harvest. Yitzchak thanks HaShem for blessing his land and faithfully tithes the crop. Yitzchak's wealth, success, and honor continue to multiply until he becomes the most prosperous man in the land. Follow the ways of Yitzchak and enjoy the unbounded blessings of HaShem.
(Based on the commentary of the RaMad Valli)